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Effect of albumin binding on the hepatic transport of rose bengal: surface-mediated dissociation of limited capacity.
We have studied the steady-state removal of rose bengal by perfused rat livers to decide whether the tight association of this anion with albumin is consistent with the conventional view that onlyExpand
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Palmitate uptake by hepatocyte monolayers. Effect of albumin binding.
The uptake of 14C-palmitate by rat liver cell monolayers is depressed by binding of the fatty acid to albumin. When the uptake flux is divided by the concentration of free palmitate in the bathingExpand
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Effect of a transported ligand on the binding of albumin to rat liver cells.
Organic anions destined for hepatic uptake often bind to albumin in the circulation. Because albumin binds to liver cells but is not transported, we suggest that sites on the hepatocyte surfaceExpand
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