W-M Deng

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BACKGROUND Dystroglycan (Dg) is a transmembrane protein that is a part of the Dystrophin Glycoprotein Complex (DGC) which connects the extracellular matrix to the actin cytoskeleton. The C-terminal end of Dg contains a number of putative SH3, SH2 and WW domain binding sites. The most C-terminal PPXY motif has been established as a binding site for(More)
  • Postdoctoral Fellow, Poulton Js, Huang Yc, Smith L, Sun J Leake, N Schleede +14 others
  • 2014
APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation. Regulation of Wnt signaling by the tumor suppressor APC does not require ability to enter the nucleus nor a particular cytoplasmic localization. Defining components of the Beta-Catenin destruction complex and exploring its regulation and mechanisms of(More)
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