W. K. H. Wong

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PURPOSE To perform a comprehensive study on organ absorbed doses and effective doses from cone beam computed tomography (CBCT) for three different treatment sites. METHODS AND MATERIALS An extensive set of dosimetric measurements were performed using a widely used CBCT system, the On-Board Imager (OBI). Measurements were performed using a female(More)
The purpose of this study was to investigate the potential benefits of using triple-arc volumetric-intensity modulated arc radiotherapy (RapidArc (RA)) for the treatment of early-stage nasopharyngeal carcinoma (NPC). A comprehensive evaluation was performed including plan quality, integral doses, and peripheral doses. Twenty cases of stage I or II NPC were(More)
BACKGROUND AND PURPOSES To develop a dose-volume-based Plan Quality Index for IMRT plans. MATERIALS AND METHODS This study used a H(ealthy) Tissue Conformity Index to describe the overall plan conformity, a M(erit) function to describe the target coverage and a P(enalty) function to evaluate doses to critical organs. The Euclidean distance (PQI) between(More)
OBJECTIVE To evaluate and optimize the parameters used in multiple-atlas-based segmentation of prostate cancers in radiation therapy. METHODS A retrospective study was conducted, and the accuracy of the multiple-atlas-based segmentation was tested on 30 patients. The effect of library size (LS), number of atlases used for contour averaging and the contour(More)
The use of noncoplanar intensity-modulated radiation therapy (IMRT) might result in better sparing of some critical organs because of a higher degree of freedom in beam angle optimization. However, this can lead to a potential increase in peripheral dose compared with coplanar IMRT. The peripheral dose from noncoplanar IMRT has not been previously(More)
We attempted to develop a method to compute the normal tissue complication probability (NTCP) of various critical organs from combined intensity-modulated radiotherapy (IMRT) and stereotactic radiotherapy (SRT) boost treatment of nasopharyngeal carcinoma (NPC), with the aid of a nonlinear image registration method. The SRT's planning computed tomography(More)
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