W Groebke-Lorenz

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From 1980 to 1987 an epidemiologic survey was conducted in northwestern Switzerland (population 523,000) with the aim of registering as many MS cases as possible. The prevalence for the entire region was 142 per 100,000, with a maximum of 164/100,000 in the city of Basle. Extrapolation suggests there are more than 8000 MS patients living in Switzerland.(More)
The neurological symptoms of patients with multiple sclerosis are located to four brain areas and are compared with the demonstrated Magnetic Resonance Imaging (MRI) lesions. Areas mostly involved are the centrum semiovale, the periventricular space, the cerebellum and the brain stem. There is a good correlation of the different clinical locations and the(More)
88 patients aged 22-70 (mean 44) years, presenting with symptoms and/or signs of multiple sclerosis, were investigated by MRI for the purpose of revealing MS-like lesions. 54% of all patients had MRI scans suggestive of MS. Patients with clinically definite MS had MS-suggestive lesions in 85% of cases, and none was normal. In patients with possible signs or(More)
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