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OBJECTIVES To determine whether offspring of centenarians acquired protection from age-related diseases. DESIGN Case-control study. SETTING The study was part of the Longevity Genes Project at Albert Einstein College of Medicine. PARTICIPANTS Centenarians (n=145), offspring of centenarians (n=180), and spouses of the offspring of centenarians (n=75)(More)
BACKGROUND Families of centenarians have high levels of plasma high-density lipoprotein (HDL) cholesterol, which may have neurological as well as cardiovascular protective effects during aging. Because plasma HDL level declines progressively with aging, we examined whether centenarians with higher plasma HDL levels have better cognitive function. METHODS(More)
DOI 10.1007/s00761-011-2076-y Online publiziert: 19. Juni 2011 © Springer-Verlag 2011 K. Damm1 · I. Barth2 · W. Greiner3 · R. Kreienberg4 · N. Maass5 · C. Riederer6 1 Institut für Versicherungsbetriebslehre, Forschungsstelle für Gesundheitsökonomie, Gottfried Wilhelm Leibniz Universität Hannover 2 GWQ Serviceplus AG, Düsseldorf 3 Abteilung für(More)
BACKGROUND Disease Management Programmes (DMP) are intended to improve the quality of the medical care of chronically sick patients and at the same time to keep stable or to reduce the costs to the healthcare system. The effectiveness of a DMP was evaluated by means of an accompanying study. METHOD Within the framework of the DMP, the patients were(More)
BACKGROUND Concepts of quality of life are gaining in increasing significance as measures of outcome, both in medicine as well as in economics. One of the relevant questionnaires is the FLA ("Fragebogen zur Lebensqualität bei Asthma"), a disease-specific instrument for measuring the quality of life of asthma patients. This questionnaire was supplemented(More)
Kiefern-Kernholz läßt sich nach dem sauren Sulfitverfahren nicht aufschließen, da Kondensationsreaktionen zwischen dem im Kernholz vorhandenen Pinosylvin und Lignin ablaufen, die einen hohen Rejectanteil zur Folge haben. An aus Kiefern-Kernholz isoliertem Pinosylvin, das unter den Bedingungen eines Sulfitaufschlusses bei pH-Werten zwischen 1,7 und 4,2(More)
The main focus of this paper is on the architectural and implementation issues of a prototype of a low-level image segmentation architecture (LISA). LISA performs real-time (20 Mpixels/sec) gray-level image segmentation, i.e., assignment of image pixels to a few user-selected classes. A decision-theoretic pattern-recognition approach is used, which is(More)
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