W Godowicz

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Spleen cell graft-versus-host (GVH) reactivity was determined in male and female, either virgin or breeder, Long-Evans (LE) rats from 3 to 24 months of age. The tests of a regional (popliteal lymph node enlargement index) and a systemic (splenomegaly index, mortality assay) GVH reaction was used. Although the GVH reactivity declined with age in both sexes,(More)
Regional graft versus host (GVH) reaction in mice induced by injection of parental strain spleen cells into the footpad of F1, recipients, was measured 7 days later by a popliteal lymph node (PLN) enlargement index. Young, 6-week-old F1 hosts can be used for studying the age- and sex-dependent GVH reactivity of parental strain donors. On the other hand,(More)
Cadmium administered intraperitoneally to male mice from a cadmium-sensitive KE strain brought about a decrease in thickness of the cortical bone layer accompanied by osteoporosis and widening of the marrow cavity. The extent of these changes was assessed by calculating the cortical index. No differences were observed between animals examined four months(More)
The mechanical strength at bending was examined in 26 femoral bones prepared from human corpses. The obtained data was compared with the cortical index (CI). The study demonstrates high correlation between CI and mechanical strength of the corpus as well as the collum of the examined bone, which means that CI is a good criterion in assessing biological age(More)
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