W. D. Fraser

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STUDY QUESTION What is the effect of maternal exposure to perfluorooctane sulfonate (PFOS), perflurooctanoic acid (PFOA) and perfluorohexane sulfonate (PFHxS) on female fecundity? SUMMARY ANSWER Increasing concentrations of PFOA or PFHxS in maternal plasma were associated with reduced fecundability and infertility. WHAT IS KNOWN ALREADY Perfluorinated(More)
The standing steadiness and postural tremor of seven male volunteers were examined during slow and rapid induction of hypoxia. Spectrum analysis of position coordinates and tremor data generated from a quartz multicomponent force measuring platform and a tremor transducer showed that postural tremor (pt) and anteroposterior sway (ay) increased significantly(More)
The controversy regarding the effects of mild hypoxia on learning performance needs to be resolved, since this may be affecting flight operations and safety. This study examined the ability to learn new tasks at low altitudes. Naive subjects (n = 144) performed spatial orientation (Manikin), serial choice reaction time (SCRT) and logical reasoning(More)
Positive pressure breathing (PPB) is a survival system that delivers high-pressure oxygen and body counterpressure in the event of cockpit depressurization at high altitude, but the ability of aircrew to perform an emergency "get-me-down" maneuver with this system is unknown. To address this question, a serial choice reaction time (RT) task was administered(More)
A model of short term cardiovascular regulation was discussed. The physiological response to acceleration stress were studied. Results showed that a supine to standing transition leads to a substantial drop in central arterial pressure (CAP), cardiac output (CO), central venous pressure (CVP) and cerebral perfusion unless reflexes are active. Mathematical(More)
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