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Low doses of serotonin potentiated immobility durations in 2 1/2-week-old chickens (Gallus gallus) while high doses attenuated the response. Cyproheptadine, a serotonergic antagonist, eliminated increases generated by low doses of serotonin and reduced durations in control subjects, but had no effect on the attenuation produced by high doses of the drug.… (More)
The effects of low and high doses of serotonin on tonic immobility (TI) duration and susceptibility in 10- and 45-day-old chickens were examined. High doses of serotonin reduced the number of inductions required to produce TI, regardless of the subject's age. In contrast, low and high doses of serotonin produced biphasic increases and decreases in TI… (More)