W. Bradley Barbazuk

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The bacteriophage population is large, dynamic, ancient, and genetically diverse. Limited genomic information shows that phage genomes are mosaic, and the genetic architecture of phage populations remains ill-defined. To understand the population structure of phages infecting a single host strain, we isolated, sequenced, and compared 627 phages of(More)
BACKGROUND The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various filtering methods to select against high-copy sequence in DNA clone libraries. The standard model for random sequencing, Lander-Waterman theory, does not account for two important(More)
The large size of the maize genome and the expectation that most of the genome is represented by repetitive elements is a challenge to standard genome sequencing techniques. Genome-filtration sequencing techniques may target gene-rich regions in the genome. Two such approaches, methylation filtration and high Cot selection, may provide rapid and(More)
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