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Absence of functional FMRP causes Fragile X syndrome. Abnormalities in synaptic processes in the cerebral cortex and hippocampus contribute to cognitive deficits in Fragile X patients. So far, the potential roles of cerebellar deficits have not been investigated. Here, we demonstrate that both global and Purkinje cell-specific knockouts of Fmr1 show(More)
We describe three methods to determine a faithful representation of small dimension for a finite-dimensional nilpotent Lie algebra over an arbitrary field. We apply our methods in finding bounds for the smallest dimension µ(g) of a faithful g-module for some nilpotent Lie algebras g. In particular, we describe an infinite family of filiform nilpotent Lie(More)
a r t i c l e i n f o a b s t r a c t We develop a practical algorithm to decide whether a finitely generated subgroup of a solvable algebraic group G is arithmetic. This incorporates a procedure to compute a generating set of an arithmetic subgroup of G. We also provide a simple new algorithm for integrality testing of finitely generated solvable-by-finite(More)
Acknowledgement We would like to thank the many people who have made contributions of various kinds to the development of GAP since 1986, in particular: The following list gives the authors, indicated by A, who designed the code in the first place as well as the current maintainers, indicated by M of the various modules of which GAP is composed. Since the(More)
The glycosylation of the acute phase glycoprotein oq-acid glycoprotein (AGP) in human sera is subject to marked changes during acute inflammation as a result of the cytokine-induced hepatic acute phase reaction. The changes described thus far comprise alterations in the type of branching of the carbohydrate structures as revealed by increased reactivity of(More)
Acknowledgement We would like to thank the many people who have made contributions of various kinds to the development of GAP since 1986, in particular: The following list gives the authors, indicated by A, who designed the code in the first place as well as the current maintainers, indicated by M of the various modules of which GAP is composed. Since the(More)
Acknowledgement We would like to thank the many people who have made contributions of various kinds to the development of GAP since 1986, in particular: The following list gives the authors, indicated by A, who designed the code in the first place as well as the current maintainers, indicated by M of the various modules of which GAP is composed. Since the(More)
Acknowledgement We would like to thank the many people who have made contributions of various kinds to the development of GAP since 1986, in particular: The following list gives the authors, indicated by A, who designed the code in the first place as well as the current maintainers, indicated by M of the various modules of which GAP is composed. Since the(More)
Acknowledgement We would like to thank the many people who have made contributions of various kinds to the development of GAP since 1986, in particular: The following list gives the authors, indicated by A, who designed the code in the first place as well as the current maintainers, indicated by M of the various modules of which GAP is composed. Since the(More)
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