W. A. Hadler

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Experimental inoculation of Mycobact erium lepme murium into the golden hamster, first done by Balfour-Jones, produces a generalized infection of slow but progressive evolution, with lesions in various organs (2,4,14,15). The Chinese hamster, however, is apparently not susceptible to this infection (13). Observations on this infection of the hamster have(More)
The benzidine technique for histochemical detection of the SO4 ion was studied analytically on filter paper strips loaded with 0.02 ml of solutions of sulfate containing and sulfate free substances. The influence of the benzidin solution pH on the SO4 and PO4 ion precipitation was analysed and the experimental condition where the SO4 ion was specifically(More)
The vitamin D transepidermis absorption was studied by means of a histochemical technique suitable to detect this vitamin and to discriminate it from cholesterol and its esters. Such technique shows vitamin D inside the mast cell granules. As the mast cell granules contain metachromatic substances its own histochemical reactivity must be previously blocked(More)
By using the benzidine reaction, on filter paper strips loaded with catalases, peroxidases, porphyrins, haemic iron compounds and iron salts, it was possible to establish 2 histochemical techniques able to detect and discriminate catalases and peroxidases. Spot test analytical studies show that only peroxidases oxidize benzidine in presence of a 0.0015 M(More)
In rats injected with DPH the morphological changes induced in the thymus and lymph nodes were studied. In the thymus, features suggesting block of cellular differentiation were found, and in lymph nodes depletion of the paracortical zone and intense plasma cell hyperplasia could be observed. The correlation of these findings with the functional changes in(More)
1. Carbon fiber reinforced carbon (CFRC) was implanted in rats as particles measuring 30 microns or 11 microns, denoted as CFRC-A and CFRC-B, respectively. Titanium (Ti) and vitreous carbon (VC) were used as controls. Ti was used with the same particle size as CFRC (Ti-A or Ti-B). The VC particles measured 11 microns. All materials were separately(More)
A technique to detect tocopherol histochemically was proposed in basis on the following schedule: 1. toluidine blue and Schiff reagent negativity before a suitable oxidation; 2. performic acid-toluidine blue and performic acid-Schiff reagent positivity after fixing in formalin-CaCl2; 3. performic acid-toluidine blue and performic acid-Schiff reagent(More)