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The research identified rye chromosome 4R arms associated with good pollinator traits, and demonstrated possible use of rye genetic resources to develop elite pollinators for hybrid wheat breeding. Bread wheat (Triticum aestivum) is a predominantly self-pollinating plant which has relatively small-sized anthers and produces a low number of pollen grains.(More)
Studies in type 1 diabetes indicate potential disease heterogeneity, notably in the rate of β-cell loss, responsiveness to immunotherapies, and, in limited studies, islet pathology. We sought evidence for different immunological phenotypes using two approaches. First, we defined blood autoimmune response phenotypes by combinatorial, multiparameter analysis(More)
With early life likely to have existed in a hot environment, enzymes had to cope with an inherent drop in catalytic speed caused by lowered temperature. Here we characterize the molecular mechanisms underlying thermoadaptation of enzyme catalysis in adenylate kinase using ancestral sequence reconstruction spanning 3 billion years of evolution. We show that(More)
UNLABELLED A cracked tooth is a common presentation in general dental practice. It may be difficult to diagnose, owing to the variations in the clinical presentation.The symptoms that result from a cracked tooth have given rise to the term Cracked Tooth Syndrome (CTS).This article reviews and discusses the clinical signs, symptoms and the management of CTS.(More)
Those who suffer from Narcissistic Personality Disorder or from Borderline Personality Disorder (Henceforth to be referred to as NPD and BPD individually and as BP/NP as a group) tend to employ an array of both normal and abnormal defense mechanisms, which are automatic mental responses designed to protect the ego from stress, anxiety or conflict. However,(More)
Bread wheat (Triticum aestivum L.) is one of the most important crops for human nutrition. It is estimated that yield improvements associated with hybrid vigour in wheat range from 5% to over 20%. However, due to the floral structure and cleistogamous characteristics of wheat, grains are predominantly produced by self-pollination. In order to facilitate(More)
Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835–3845 DOI: 10.2337/db15-er09a Sefina Arif, Pia Leete, Vy Nguyen, Katherine Marks, Nurhanani Mohamed Nor, Megan Estorninho, Deborah Kronenberg-Versteeg, Polly J. Bingley, John A. Todd, Catherine Guy, David B. Dunger, Jake Powrie, Abby Willcox,(More)
Metabolomics is an emerging scientific field focusing on compounds, also known as metabolomes that are produced by biologic systems. Metabolomes represent phenotypic end-products of living entities, and are of particular interest as they represent a novel group of biomarkers that can be used for diagnosis, monitoring response to treatments, and more(More)
Electrical stimulation of tissues induces cell alignment, directed migration, extended processes, differentiation, and proliferation, but the mechanisms involved remain largely unknown. To reveal effects of electric fields (EF) through the media on cell behavior, voltage (7.45 – 22 V), current density (36 – 106 mA/cm 2 ), duration (2 – 24 hrs), and(More)
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