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Mutations in the neurofibromatosis 2 (NF2) gene with the resultant loss of expression of the NF2 tumor suppressor schwannomin are one of the most common causes of benign human brain tumors, including schwannomas and meningiomas. Previously we demonstrated that the hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) strongly interacts with(More)
CAPTCHAs are a standard security mechanism used on many websites to protect online services against abuse by automated programs, or bots. The purpose of a CAPTCHA is to distinguish whether an online transaction is being carried out by a human or a bot. Unfortunately, to date many existing CAPTCHA schemes have been found to be vulnerable to automated(More)
In automated container terminals, containers are transported from the marshalling yard to a ship and vice versa by automated vehicles. The automated vehicle type studied in this paper is an automated lifting vehicle (ALV) that is capable of lifting a container from the ground by itself. This study discusses how to dispatch ALVs by utilizing information(More)
Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) is required for trafficking of cell surface receptors to the lysosome. Previously, we identified HRS as a protein that interacts with the neurofibromatosis 2 tumor suppressor schwannomin. In the present study, we established modified RT4 schwannoma cell lines that inducibly express HRS and(More)
CAPTCHAs have become a standard security mechanism that are used to deter automated abuse of online services intended for humans. However, many existing CAPTCHA schemes to date have been successfully broken. As such, a number of CAPTCHA developers have explored alternative methods of designing CAPTCHAs. 3D CAPTCHAs is a design alternative that has been(More)
In port container terminals, containers are transported between vessels and storage blocks by transporters. To improve the utilization of transporters and the operational efficiency of container terminals, the pooling strategy is widely applied, and transporters in the same pool are shared by a group of quay cranes (QCs). This paper compares various(More)
The asymmetric unit of the title salt, C7H7N2 (+)·ClO4 (-), comprises two independent formula units. The solid-state structure comprises corrugated layers of cations and of anions, approximately parallel to (010). The supra-molecular layers are stabilized and connected by C-H⋯O hydrogen bonding to consolidate a three-dimensional architecture. A close(More)