Vreni Schneider

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Proviral human immunodeficiency virus type 1 (HIV-1) DNA could be a useful marker for exploring viral reservoirs and monitoring antiretroviral treatment, particularly when HIV-1 RNA is undetectable in plasma. A new technique was developed to quantify proviral HIV-1 using a TaqMan real-time PCR assay. One copy of proviral HIV-1 DNA could be detected with(More)
We tested the hypothesis that reducing core body temperature in subjects with multiple sclerosis (MS) improves the cortical somatosensory evoked potential (SEP) response. Twenty subjects with definite MS were compared with 20 subjects without neurologic symptoms or disease. SEPs were recorded with stimulation of the tibial and median nerves unilaterally at(More)
BACKGROUND/AIMS Transactivated hepatic stellate cells (HSCs) represent the key source of extra cellular matrix (ECM) in fibrotic liver. Imatinib, a potent inhibitor of the PDGF receptor tyrosine kinase, reduces HSC proliferation and fibrogenesis when treatment is initiated before fibrosis has developed. We tested the antifibrotic potential of imatinib in(More)
The endocannabinoid (EC) system is implicated in many chronic liver diseases, including hepatitis C viral (HCV) infection. Cannabis consumption is associated with fibrosis progression in patients with chronic hepatitis C (CHC), however, the role of ECs in the development of CHC has never been explored. To study this question, anandamide (AEA) and(More)
Aims Detection of E6 and E7 mRNA transcripts has been shown to be of higher prognostic value for the evaluation of the precursor lesions of cervical carcinoma than the detection of HPV DNA in a number of pilot studies [1-3]. In particular in low grade lesions, HPV DNA testing has poor discriminating power as to the progression of CIN, thus leading to(More)
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