Volker R Rudat

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PURPOSE To analyze the relationship between pre-treatment measurements of tumor oxygen tension (pO2) and survival in advanced head and neck cancer. PATIENTS AND METHODS Eppendorf pO2 measurements in 397 patients from seven centers were analyzed using the fraction of pO2 values < or =2.5 mmHg (HP2.5), < or =5 mmHg (HP5) and median tumor pO2 (mmHg) as(More)
PURPOSE To evaluate potential prognostic factors for local control and survival after radiotherapy of metastatic spinal cord compression (MSCC). PATIENTS AND METHODS The following potential prognostic factors were investigated retrospectively in 1,852 patients irradiated for MSCC: age, sex, performance status, primary tumor, interval between tumor(More)
The objective of this expanded phase II trial was to confirm the safety results of the preceding phase I study and establish the efficacy of neoadjuvant radiochemotherapy with capecitabine in rectal cancer in a multicenter setting. 96 patients (63% male, age 34–81 years) with advanced rectal cancer (cT3–4 or cN+) from seven university centers in Germany(More)
BACKGROUND AND PURPOSE To contribute to the question whether the risk of radiation-related brachial plexopathy increases, remains constant or decreases with time after treatment. PATIENTS AND METHODS Between 12/80 and 9/93, 140 breast cancer patients received supraclavicular lymph node irradiation using a telecobalt unit. Total dose was 60 with 3Gy per(More)
Ziel dieser Arbeit ist es, den prädiktiven Charakter der angiogenen Zytokine ”basic fibroblast growth factor” (bFGF), ”vascular endothelial growth factor” (VEGF) und der Protease ”matrix metalloproteinase-2” (MMP-2) anhand serologischer Bestimmungen bei Patienten mit fortgeschrittenen Kopf-Hals-Karzinomen zu untersuchen. In den Jahren 1992–1995 wurden bei(More)
BACKGROUND The purpose of the current study was to retrospectively investigate clinical outcome and potential prognostic factors after reirradiation (Re-RT) for in-field recurrence of metastatic spinal cord compression (MSCC). METHODS Re-RT with 1 x 8 Gy (n = 48), 5 x 3 Gy (n = 29), 5 x 4 Gy (n = 30), 7 x 3 Gy (n = 3), 10-12 x 2 Gy (n = 11), or 17 x 1.8(More)
PURPOSE To identify significant prognostic factors after irradiation of metastatic spinal cord compression (MSCC) in 335 breast cancer patients. METHODS AND MATERIALS The potential prognostic factors investigated included involved vertebra, other bone metastases, visceral metastases, performance status, pretreatment ambulatory status, time until motor(More)
PURPOSE Patients with prostate cancer with metastatic spinal cord compression have better survival prognosis than other patients with MSCC and may live long enough to develop a local recurrence of MSCC. This study investigates prognostic factors and radiation schedules for functional outcome and local control of MSCC after radiotherapy in patients with(More)
Background. This study was undertaken to evaluate the impact of prognostic factors on the locoregional failure-free survival of early breast cancer patients. Methods. In this single-institutional study, 213 breast cancer patients were retrospectively analysed. Fifty-five of 213 patients were ≤40 years of age at diagnosis. The impact of patient- or(More)
Patients with cancer of unknown primary account for 10% of patients with metastatic spinal cord compression (MSCC). This retrospective study was performed to identify prognostic factors for functional outcome, local control of MSCC, and survival in 175 of such patients treated with radiotherapy alone. Investigated were nine potential prognostic factors(More)