Vladislav Pavlov

Learn More
The current first-line treatment of malignant gliomas consists in surgical resection (if possible) as large as possible. The existing tools don't permit to identify the limits of tumor infiltration, which goes beyond the zone of contrast enhancement on MRI. The fluorescence-guided malignant gliomas surgery was started 15 years ago and had become a standard(More)
BACKGROUND The standard of care for newly diagnosed glioblastoma is maximal safe surgical resection, followed by chemoradiation therapy. We assessed carmustine wafer implantation efficacy and safety when used in combination with standard care. METHODS Included were adult patients with (n = 354, implantation group) and without (n = 433, standard group)(More)
The aim of this study was to analyze the association of different clinical contributors of hypoxic-ischemic encephalopathy with NOS3 gene polymorphisms. A total of 110 children with hypoxic-ischemic encephalopathy and 128 control children were selected for this study. Association of gender, gestational age, birth weight, Apgar score, cranial(More)
BACKGROUND The study investigated if intraoperative use of carmustine wafers, particularly in combination with Stupp regimen, is a viable and safe first-line treatment option of glioblastomas. METHODS Eighty-three consecutive adult patients (50 men; mean age 60 years) with newly diagnosed supratentorial primary glioblastomas that underwent surgical(More)
Methods for separating temporally overlapping sources of neuroelectric data. Affective picture processing: event-related synchronization within individually defined human theta band is modulated by valence dimension. AR modeling of nonstationary time series by means of Kalman filtering. computation of scalp current density and coherence: a reply to Perrin.(More)
AIM To assess the dynamic of intracranial pressure (ICP), cerebral perfusion pressure (CPP), and dynamic pressure reactivity index (PRx) during intrahospital transport. MATERIALS AND METHODS There were 33 comatose patients with severe traumatic brain injury (TBI). The mean age was 36.3 ± 4.8 years (range 19-45 years), and there were 17 men and 16 women.(More)
BACKGROUND The management of gliomas is based on precise histologic diagnosis. The tumor tissue can be obtained during open surgery or via stereotactic biopsy. Intraoperative tissue imaging could substantially improve biopsy precision and, ultimately, the extent of resection. OBJECTIVE To show the feasibility of intraoperative in vivo probe-based confocal(More)
An effective low-costs olution to determine characteristic features of objectsfrom asimple infrared diode array,working on the reflection light scanner principle and using the fusion of amplitude informationt od etect and characterize objects,has been designed. Essentially,two arraysofseveral emitter-receiver pairs are mounted on opposite sidesofthe area of(More)