Vladimir Yusupov

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Remobilization to the atmosphere of only a small fraction of the methane held in East Siberian Arctic Shelf (ESAS) sediments could trigger abrupt climate warming, yet it is believed that sub-sea permafrost acts as a lid to keep this shallow methane reservoir in place. Here, we show that more than 5000 at-sea observations of dissolved methane demonstrates(More)
This paper is aimed at revealing the mechanisms of therapeutic effects stimulated by a medium power (1–10 W) fiber laser induced hydrodynamics in water-saturated bio-tissues. Modern laser medical technologies widely employ delivery of laser light to irradiated tissues via optical fibers. Optical fiber easily penetrates through needle and endoscopic(More)
We studied the dose-dependent induction of in vivo adaptive response in the bone marrow and blood of mice exposed to low-intensity radiation of He-Ne laser (633 nm) and X-ray radiation by the severity of cytogenetic injury and intensity of ROS production, respectively. Induction of the adaptive response in mice preexposed to He-Ne laser and X-ray radiation(More)
Sustained release of methane (CH(4)) to the atmosphere from thawing Arctic permafrost may be a positive and significant feedback to climate warming. Atmospheric venting of CH(4) from the East Siberian Arctic Shelf (ESAS) was recently reported to be on par with flux from the Arctic tundra; however, the future scale of these releases remains unclear. Here,(More)
We present a theoretical model for laser cutting of biological tissue by a strongly heated fiber tip with a highly absorbing coating. A significant dependence of the cutting speed and cutting depth on the inclination angle of the scalpel to the surface when scattering exceeds absorption in the biological tissue is shown. Experimental evidences of this(More)
We studied the effect of exposure to helium-neon laser (dose range 0.16-50 mJ/cm2) on activation of natural protection reserve in mice using the adaptive response test. DNA comets method revealed a protective response manifested in DNA damage level in whole blood leukocytes of mice and in lymphoid organs by the thymus and spleen weight index; preexposure to(More)
The proliferative activity of HaCaT keratinocytes and rat mesenchymal stromal cells (MSCs) in rats subjected to femtosecond laser pulses has been studied. The growth medium were exposed to laser pulses with a wavelength of 590 nm and duration of 30 fs. Proliferative activity was assessed from the cell number 1 day after the exposure. Cell proliferation in(More)
We studied the effects of physical factors (acoustic impulses of laser-induced hydrodynamics, AILIH, and EHF-radiation) on the formation of heterotopic bone marrow organs. Suspension of precipitated mouse bone marrow cells was exposed to AILIH and EHF or their combinations (AILIH+EHF, EHF+AILIH). The developed tissue engineering constructions (gelatin(More)
146 Monochromatic (laser) and quasimonochromatic light in the range 600–900 nm can stimulate metabolic processes in eukaryotes [1–4]. Despite the fact that this phenomenon has already been successfully used for decades in medical practice (low intensity laser therapy), the range of possible applications of this type of radiation is still expanding, and the(More)
We studied the effect of laser-induced hydrodynamic on viability of Colo-26 murine colon carcinoma cells in vitro. Laser-induced hydrodynamics was generated by a laser (λ=1.56 μ, power 3 W, 5 min exposure); to this end, the fiber end was submersed into a buffer above the cell monolayer. It was found that laser-induced hydrodynamics destructed the monolayer(More)
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