Vladimir V. Zakharov

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A total of 52 patients with Parkinson's disease (PD), 11 with presumptive Alzheimer's disease (AD), and 20 healthy subjects were studied; subjects were aged 55-74 years. Neurological symptoms were assessed quantitatively, and the state of higher mental processes were evaluated using the Luriya method. A number of memory tests were also used. These studies(More)
A total of 88 patients with progression of Parkinson's disease (PD) were studied. Cognitive impairments (CI) in PD were in most cases progressive in nature, predominantly because of increases in the severity of dysregulatory and neurodynamic disorders, impairments to visuospatial functions, and, in some cases, deficits in nominative speech function. A high(More)
Neurocognitive functions have been studied in 100 patients with Parkinson's disease (PD). PD was associated with cognitive impairment due to frontal lobes dysfunction, with hippocampus and right hemisphere involvement in advanced stages of the disease. Severity of cognitive impairment increased simultaneously with severity of movement disorder. Patient's(More)
40 Начиная с 90-х годов ХХ века все более уси-ливается интерес врачей и исследователей к не-дементным когнитивным нарушениям в пожилом возрасте. В настоящее время общепризнано, что развитию деменции как при нейродегенеративном, так и при сосудистом поражении головного мозга предшествует весьма длительный период вначале бессимптомного, а затем(More)
Frequency of clinical and psychological peculiarities of moderate (mild) cognitive impairment (MCI) in cerebral vascular insufficiency (CVI) was studied in 42 patients, mean age 67.7 +/- 7.7 years. Along with neurological examination, a battery of psychiatric and neuropsychological scales and tests was used. MCI was diagnosed in 28 (66.7%) patients. In 20(More)
The article presents analysis of clinical case of and review of literature on "ALS-dementia complex", a combination of ALS syndrome and dementia predominantly of frontal lobe type. The review of literature contains discussion on the problem of lobe dementia, analysis of relation of ALS-dementia syndrome and the following diseases: Alzheimer, Pick,(More)
Neurodegenerative diseases accompanied by cognitive impairment (dementia with Levy's bodies--DLB and Alzheimer's disease--AD) and others) are becoming more widespread due to increasing population life expectancy. The paper addresses use of cognitive event-related potential P300 to verbal and nonverbal stimuli with an assessment of interhemispheric asymmetry(More)