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The forkhead box m1 (Foxm1) transcription factor is essential for initiation of carcinogen-induced liver tumors; however, whether FoxM1 constitutes a therapeutic target for liver cancer treatment remains unknown. In this study, we used diethylnitrosamine/phenobarbital treatment to induce hepatocellular carcinomas (HCCs) in either WT mice or(More)
—The sensitivity of application specific integrated circuits (ASICs) to the single event effects (SEE) can induce failures of the systems which are exposed to increased radiation levels in the space and on the ground. This paper presents a design methodology for a full fault tolerant ASIC that is immune to the single event upsets (SEU) in sequential logic,(More)
Expansions of (GAA)n repeats within the first intron of the frataxin gene reduce its expression, resulting in a hereditary neurodegenerative disorder, Friedreich's ataxia. While it is generally believed that expanded (GAA)n repeats block transcription elongation, fine mechanisms responsible for gene repression are not fully understood. To follow the effects(More)
The fast grow of expectations from robots and the technical obstacles the robot developers face when trying to meet the requests, force an orientation towards designing and controlling robots by following biological paragons. This tendency increases interest in human-robot analogy, and the present work is a part of this stream. The paper questions the(More)
In this work numerical simulation and measurements of three-dimensional radiation patterns of a mobile handset model in the presence of a human head phantom were performed at 1800 MHz. Based on theoretical and experimental results, the influence of the human head on the radiation efficiency of the handset has been investigated as a function of the handset(More)