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Spin-transfer torque magnetic random access memory (STT-MRAM) is a novel, magnetic memory technology that leverages the base platform established by an existing 100+nm node memory product called MRAM to enable a scalable nonvolatile memory solution for advanced process nodes. STT-MRAM features fast read and write times, small cell sizes of(More)
Prevalence of glucose intolerance and other noncommunicable diseases has been examined in subjects aged 35 years and over in semirural and urban communities in the Fergana Valley in the eastern part of Uzbekistan, Central Asia. Diabetes and impaired glucose tolerance (IGT) were diagnosed according to the recommendations of the latest WHO Study Group on(More)
Involvement of neurotransmitter receptors and translation and transcription processes in reconsolidation of conditioned food aversion memory was investigated in experiments on edible snails. Injections of neurotransmitter receptor antagonists and protein synthesis inhibitors before the reminder session were found to induce amnesia that was characterized by(More)
Experiments on the common snail were performed to study the influences of serotonin and glutamate receptor antagonists on the processes of reactivation of an associative habit consisting of refusing a particular type of food. Twenty-four hours after training, animals were injected with the non-selective serotonin receptor antagonist methiothepin (0.1(More)
Current considerations suggest that the mechanisms of long term memory are based on the changes of the neuronal genetic algorithms. Process of the enzyme DNA methylation have great importance to the differential genes expression, and is likely to be one of the key mechanisms of the consolidation and memory storage. The present study aimed to investigate the(More)
Electrophysiological parameters and bound calcium (Ca(b)) level dynamics during sensitization development or conditioning of food aversion were studied in the command neurons of defense behaviour in the snail Helix lucorum. Responses evoked by a testing sensory stimulus were facilitated 50-60 min after the first sensitizing stimulation, while conditioned(More)
We found previously that the inhibition of NMDA glutamate receptors during food aversion conditioning reactivation initiated disruption of long-term memory. In this work the dynamics of amnesia development was investigated. MK-801 (NMDA receptor antagonist) was injected into snail body cavity 24 hours after food aversion conditioning and conditioned food(More)
The effects of serotonin and glutamate receptor antagonists on conditioned food aversion memory reconsolidation were studied in experiments on edible snails. Injections of NMDA and AMPA glutamate receptor antagonists to trained snails before the reminder were found to induce the development of “irreversible” amnesia: repeated training of these animals was(More)
According to current concepts, long-term memory is based on structural-functional changes in particular synaptic connections between neurons in the brain (synapse-specific plasticity), which depend on the processes of translation and transcription. Studies on neurons in the mollusk Aplysia and the mammalian hippocampus have addressed a mechanism of(More)
Memory is destabilized during retrieval-induced reconsolidation and can therefore be disrupted or modified. In the present study, we examined the role of translation and transcription processes in long-term food aversion memory reconsolidation in the snail Helix lucorum. The administration of the protein synthesis inhibitor anisomycin followed by a(More)