Vladimir Baláz

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Platelet aggregation and ATP release were simultaneously measured in platelet-rich plasma samples obtained from humans of various age. In subjects aged over 59 years, an increase was found in platelet sensitivity to ADP and collagen as well as elevated aggregation amplitudes 5 min after induction with low concentrations of the aggregation agents. At 1(More)
Male Wistar specific-pathogen-free rats aged 2, 7, 17, 30, 60, 120, 200, 360 and 600 days, all killed in experiment on the same day, were examined. The body weight significantly increased until the 200th day, the weight of adrenals until the 120th day and the adrenal protein content until the 30th day of life. The adrenaline content of the adrenals(More)
During the period of a low vitamin C intake (approximately equal to 20 mg per day) ascorbic acid in a dose of 2 x 500 mg per day was administered to 82 men and women aged 50-75 years. A correlation of plasma cholesterol levels determined before and after a three months' administration of ascorbic acid showed the effect of vitamin C to be dependent on the(More)
13 month-old and 25 month-old Wistar rats were exposed to immobilisation stress and compared with a control group of animals. The most impressive influence was found in mitochondria but there were not any significant changes of myofibrils. The number of mitochondria decreased significantly as well as their relative cytoplasmic volume. Absolute mitochondrial(More)
Fatty acid (FA) profiles of total serum lipids were determined by capillary gas chromatography in Type 2 diabetic patients (NIDDM) with diverse types of hyperlipidemia. In patients with hypertriglyceridemia (DM-HTG) and combined hypertriglyceridemia and hypercholesterolemia (DM-HLP), a significantly different total FA composition was found compared with(More)
The storage of actomyosin isolated from bovine heart for one week either at +4 degrees or frozen at -5 degrees results in deep structural changes in the molecule of actomyosin, while storage of the actomyosin at the mentioned temperatures in the presence of sodium glutamate preserved the characteristic structure of actomyosin molecule as revealed by(More)
Ivage geese were fattened for 6 weeks; 3-5 weeks later, with diminished food intake, they developed degenerative ultrastructural changes of the myocardium: frequent myelin-like bodies, fragmentation and sometimes contractive bundles of myofibrils, lipid droplets, nuclear lobulation and focal cytolysis were observed. Adaptive changes included hypermetabolic(More)
The composition of total fatty acids was analyzed in the serum of subjects with normal lipid and glycide metabolism, aged 20 to 89 years. A mathematico-empirical procedure was applied and on using the method of multiple linear regression the formulas of biological function age, designated as lipid age, were established, with individual serum fatty acids and(More)