Vladimír Brodan

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The effect of 120-h sleep deprivation on the activity of selected enzymes of energy metabolism in skeletal muscle was studied in seven healthy volunteers. The results showed a significant decrease in the activity of malate dehydrogenase, citrate synthase, glycerol-3-phosphate dehydrogenase and lactate dehydrogenase. Triosephosphate dehydrogenase,(More)
The effect of 5 days of sleep deprivation on the circadian rhythm of serum iron was studied in a group of six healthy male volunteers. The results were compared with a control group of five individuals, whose normal sleep cycle was preserved, but whose daily regimen was otherwise identical with the sleep deprivation group. Their biorhythm was processed(More)
By comparison with controls the investigation of 47Ca absorption and excretion kinetics after oral administration to patients with Billroth I gastrectomy (without milk intolerance) showed no differences in excretion of the isotope in urine and stool or in retention in the body. Patients with Billroth II gastrectomy had a higher degree of isotope excretion(More)
In nine patients with ischaemic heart disease at rest and during pacing differences of free plasma amino acids, lactate, ammonia and uric acid between arterial blood and blood in the coronary sinus (a-cs differences) were investigated. At rest one single significant difference was found, i.e. a positive a-cs difference in aspartate. During pacing(More)