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  • Mariana Machado Pereira, Amaranta Muniz Malvezzi, +7 authors Osvaldo P de Melo Neto
  • Medicine, Biology
  • Molecular and biochemical parasitology
  • 2013 (First Publication: 1 August 2013)
  • The eukaryotic eIF4F complex, the cap binding complex, functions during translation initiation through interactions mediated by its three subunits (eIF4E, eIF4G and eIF4A), other initiation factorsExpand
  • Martin Roffé, Glaucia Noeli Maroso Hajj, Hátylas Felype Zaneti de Azevedo, Viviane de Souza Alves, Beatriz A. Castilho
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2013 (First Publication: 27 February 2013)
  • Background: IMPACT inhibits GCN2, a kinase that directs stress remedial responses by attenuating translation and controls feeding behavior and memory. Results: Neuronal IMPACT is developmentallyExpand
  • Warrison A. Andrade, António Martins da Silva, +7 authors Ricardo T Gazzinelli
  • Biology, Medicine
  • Genes and Immunity
  • 2010 (First Publication: 21 January 2010)
  • Guanine-nucleotide exchange factors (GEFs) stimulate the intrinsic GDP/GTP exchange activity of Ras and promote the formation of active Ras–GTP, which in turn controls diverse signalling networksExpand
  • Larissa S. Carnevalli, C. Pereira, +6 authors B. Castilho
  • Biology, Medicine
  • The Biochemical journal
  • 2006 (First Publication: 1 July 2006)
  • In response to different cellular stresses, a family of protein kinases phosphorylates eIF2alpha (alpha subunit of eukaryotic initiation factor-2), contributing to regulation of both general andExpand
  • Jianling Xie, Viviane de Souza Alves, Tobias von der Haar, Louise O'Keefe, Christopher G. Proud
  • Medicine, Biology
  • Current Biology
  • 2019 (First Publication: 4 March 2019)
  • Maintaining accuracy during protein synthesis is crucial to avoid producing misfolded and/or non-functional proteins. The target of rapamycin complex 1 (TORC1) pathway and the activity of the proteinExpand
  • Marco Aurélio Soares, Roberta Amália de Carvalho Araújo, +9 authors Patrícia Silva Cisalpino
  • Biology, Medicine
  • BMC Genomics
  • 2015 (First Publication: 12 May 2015)
  • BackgroundSpecies from the Paracoccidioides complex are thermally dimorphic fungi and the causative agents of paracoccidioidomycosis, a deep fungal infection that is the most prevalent systemicExpand