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Helicobacter pylori infection is very common in Chilean adults, but the age-related prevalence, risk factors for infection, and mode of transmission in Chilean children are unknown. An ELISA was used to test for H. pylori antibodies in 1815 Chileans < 35 years of age. Seropositivity was > 60% in lower socioeconomic groups. H. pylori seropositivity(More)
A passive haemagglutination assay measuring antibody to highly purified Vi antigen, known to be sensitive and specific for the detection of chronic Salmonella typhi carriers in a non-endemic area, was assessed in an endemic area. A reciprocal serum Vi antibody titre of 160 was found to have a sensitivity of 75%, specificity of 92%, and a high predictive(More)
The emergence of a novel strain of influenza virus A (H1N1) in April 2009 focused attention on influenza surveillance capabilities worldwide. In consultations before the 2009 outbreak of influenza subtype H1N1, the World Health Organization had concluded that the world was unprepared to respond to an influenza pandemic, due in part to inadequate global(More)
BLOCKINfocused BLOCKINattention BLOCKINon BLOCKINinfluenza BLOCKINsurveil-lance capabilities worldwide. In consultations before the 2009 BLOCKINoutbreak BLOCKINof BLOCKINinfluenza BLOCKINsubtype BLOCKINH1N1, BLOCKINthe BLOCKINWorld BLOCKINHealth Organization had concluded that the world was unprepared to respond to an influenza pandemic, due in part to(More)
BACKGROUND The role of demographic factors, climatic conditions, school cycles, and connectivity patterns in shaping the spatio-temporal dynamics of pandemic influenza is not clearly understood. Here we analyzed the spatial, age and temporal evolution of the 2009 A/H1N1 influenza pandemic in Chile, a southern hemisphere country covering a long and narrow(More)
UNLABELLED INTRODUCTION AND SETTING: Our analysis compares the most comprehensive epidemiologic and virologic surveillance data compiled to date for laboratory-confirmed H1N1pdm patients between 1 April 2009 - 31 January 2010 from five temperate countries in the Southern Hemisphere-Argentina, Australia, Chile, New Zealand, and South Africa. OBJECTIVE We(More)
The epidemiologic behavior of the Invasive Meningococcal Disease (IMD) in Chile has changed. At the end of 2011, the W135 serogroup belonging to the hypervirulent clone ST-11 emerged. It affected diverse countries of the world, after the Mecca pilgrimage in 2000. In Chile, there have been 133 IMD cases during 2012. These figures represent an incidence of(More)
BACKGROUND Strategies for accelerated control of rubella and congenital rubella syndrome (CRS) in Chile included mass vaccination of women of childbearing age in 1999 but did not include vaccination of adult men. METHODS We reviewed data from Chile's integrated surveillance system for measles, rubella, and CRS from 2004 through 2009 and describe the(More)
To determine effects of school breaks on influenza virus transmission in the Southern Hemisphere, we analyzed 2004-2010 influenza-like-illness surveillance data from Chile. Winter breaks were significantly associated with a two-thirds temporary incidence reduction among schoolchildren, which supports use of school closure to temporarily reduce illness,(More)