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Hill for their valuable comments and suggestions about this research. We also thank both the Virginia Community College System and the North Carolina Community College System for providing high-quality data and expert guidance on the state contexts for this research. Abstract The annual number of certificates (non-degree awards that typically require less(More)
Pathogenic bacteria resistant to many or all antibiotics already exist. With the decline in microbiological research at pharmaceutical companies, the high rate at which resistance has evolved and spread has demanded a novel approach to addressing this critical human health issue. In the present paper, we propose a new paradigm in antibiotic discovery and(More)
The M2 isoform of pyruvate kinase is expressed preferentially in cancer cells over other pyruvate kinase isoforms. PKM2 is unique in its ability to be regulated allosterically by nutrients and growth signaling pathways, allowing cells to adapt their metabolic program to match physiological needs in different environments. Here, we discuss the role of(More)
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