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84 patients of juvenile myoclonic epilepsy (JME) of Janz were studied. Diagnosis was confirmed using clinical and electro-encephalographic (EEG) criterias. 58 (78%) patients of JME were referred as 'refractory or uncontrolled seizures'. Ignoring myoclonic episodes and non-use of activation procedures in EEG were important reasons for diagnostic delay.… (More)
Central motor conduction time (CMCT) to abductor digiti minimi (ADM) and tibialis anterior (TA) was measured in 21 patients of motor neuron disease (MND). In the upper limb, the motor pathways were inexcitable in 13 and central motor conduction time (CMCT-ADM) was prolonged in 7 sides. In the lower limbs the motor pathways were inexcitable in 10 and CMCT-TA… (More)
This study was undertaken to evaluate the role of excitatory amino acid glutamate (Glu) in the pathophysiology of motor neuron disease (MND). It was observed that blood Glu levels were significantly higher in MND patients with respect to healthy controls. The data indicate that Glu homeostasis is altered in the patients with MND.
The assessment of sustainability requires that the diverse values of the stakeholders are represented in the context-specific interpretation of sustainability and in the choice of a desired course of action. Sustainability is a broad concept, and the stakeholders in sustainability are many. In order to have effective stakeholder engagement, it is crucial… (More)
D-transposition of great arteries (D-TGA) is the most common cyanotic congenital heart disease diagnosed at birth. There is ventriculoarterial discordance leading to parallel circulation. The postnatal survival depends on intercirculatory mixing of oxygenated and deoxygenated blood at various levels through atrial septal defect, ventricular septal defect or… (More)