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Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are represented once, while a quarter of the genome corresponds to several gene families that have been greatly expanded by gene duplication, the largest family(More)
Purpose. To analyze optical coherence tomography angiography (OCTA) findings in eyes with central serous chorioretinopathy (CSC) and to compare them with those obtained with multimodal imaging. Methods. A series of consecutive patients diagnosed with CSC, underwent OCTA and multimodal imaging, including spectral domain OCT, fluorescein, and indocyanine(More)
PURPOSE To report the case of a patient with unilateral idiopathic macular telangiectasia (IMT) associated with type 3 neovascularization. METHODS Observational case report. RESULTS We describe a case of an 85-year-old woman who presented at our department with a gradual vision loss in her left eye (LE). Her best-corrected visual acuity (BCVA) was(More)
PURPOSE To describe and interpret "choroidal caverns," an unreported optical coherence tomography (OCT) finding in the choroid of patients with geographic atrophy (GA) secondary to atrophic AMD. METHODS Retrospective analysis of patients with GA. Main outcomes measures included estimation of the prevalence of choroidal caverns, their localization and(More)
AIMS To explore: a) the burden of care, and the professional and social support in relatives of patients with bipolar disorders; b) the psychosocial interventions provided to patients and their families by Italian mental health centres. METHODS 342 outpatients with a bipolar disorder and their key-relatives were randomly recruited in 26 Italian mental(More)
Purpose Drusenoid pigment epithelial detachments (PEDs) are a defined path to atrophy in age-related macular degeneration (AMD). We analyzed the relationships between retinal pigment epithelium (RPE) and drusen volume changes during the PED lifecycle, using spectral-domain optical coherence tomography (SD-OCT). Methods Twenty-one cases of drusenoid PED(More)
Appearance of medium–large drusen and reticular pseudodrusen on adaptive optics in age-related macular degeneration " British Journal of Ophthalmology, pp. bjophthalmol–2014–305 455+, Jul. 2014 T. Bek, " Fine structure in diabetic retinopathy lesions as observed by adaptive optics imaging. a qualitative study " Acta Ophthalmologica, Jun. 2014 I. Kozak, "(More)
PURPOSE To evaluate the size of type 1 choroidal neovascularization (CNV) in neovascular AMD by optical coherence tomography angiography (OCTA) and to compare with indocyanine green angiography (ICGA). METHODS Patients diagnosed type 1 CNV underwent multimodal imaging by fluorescein angiography (FA), ICGA, spectral-domain (SD)-OCT, and OCTA. Lesion size(More)
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