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Cannabis is the most widely used illegal drug in the U.S. population. Surveys have estimated that the lifetime prevalence rate for cannabis dependence is approximately 4%. Though the presence of a psychiatric disorder increases the likelihood of developing substance dependence, the field lacks data regarding the association between mental disorders and(More)
The dropout rates among cocaine abusers in outpatient treatment programs have averaged 55%. We sought to find patient predictor variables associated with early attrition. Dropouts were more likely to be African-American or Hispanic-American, younger, with an earlier onset of substance abuse. Among minorities, those with more education were less likely to(More)
BACKGROUND Atypical depression is associated with elevated rates of personality disorders. Studies have confirmed the efficacy of a several antidepressants in the treatment of atypical depression. Whether their pathological dimensions of personality diminish after benefitting from effective medication treatment is unclear. AIMS To determine the extent(More)
Unmedicated depressed outpatients were tested on dichotic syllable and complex tone tests prior to receiving 16 weekly sessions of cognitive therapy (n = 31) or 6-12 weeks of placebo treatment (n = 45). Cognitive-therapy responders had twice the right-ear (left hemisphere) advantage for syllables when compared with nonresponders but did not differ from(More)
  • V Agosti
  • Journal of affective disorders
  • 1999
BACKGROUND Results from short-term treatment studies have demonstrated the efficacy of antidepressant medications for outpatients with early-onset chronic depression. However, scant data exists regarding the long-term outcome of these patients treated for this disorder. METHODS The author conducted a one-year naturalistic follow-up study of 50 outpatients(More)
BACKGROUND Depressive disorders are commonly comorbid with alcoholism, particularly in treatment-seeking samples. If antidepressant treatment were safe and improved the treatment outcome in the subset of actively drinking alcoholics with depression, this would be of clinical importance. METHODS We conducted a randomized, 12-week placebo-controlled trial(More)
Of 60 cocaine misusers seeking outpatient treatment, 33 (55%) dropped out by 4 weeks. Dropouts were more likely to be male, Black or Hispanic, or with no history of primary depression. Completers were more likely to be White, female, or depressed. The implications of these findings and possible strategies for reducing the dropout rate are discussed.
OBJECTIVE To determine if Attention Deficit Hyperactivity Disorder (ADHD) is a risk factor for suicide attempts. METHODS Data were drawn from the National Comorbidity Replication Survey (NCS-R), a nationally representative sample of adults (N=8098). RESULTS Of the 365 adults with current ADHD, 16% attempted suicide. After controlling for the presence of(More)
Sparse data exist regarding the risks and benefits of treating bipolar-II depression with antidepressants alone. On the basis of studies of bipolar-I patients, treatment guidelines suggest antidepressants should be augmented with mood stabilizers. Whether these recommendations apply to bipolar-II is unclear. A post-hoc analysis of a double-blind study,(More)
Cannabis Dependence remains a highly prevalent disorder in the United States. Though longitudinal studies have accumulated data regarding risk factors and psychosocial correlates of habitual cannabis use, the field lacks knowledge regarding predictors of recovery in community samples. Thus we conducted a secondary data analysis of The National(More)