Vitali Henne

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Especially in patients with pancreatic carcinoma (1-5) (89%) the high molecular weight mucin CA 19-9 (MG 210 kD) shows a high specificity (98.5%) and sensitivity (up to 82%) (6-7). The mayor problem in the field of CA 19-9 diagnostics is the lack of satisfying comparability between CA 19-9 test kits: external proficiency studies (8) indicate a discrepancy(More)
We develop a multilevel algorithm for hypergraph partitioning that contracts the vertices one at a time and thus allows very high quality. This includes a rating function that avoids nonuniform vertex weights, an efficient " semi-dynamic " hypergraph data structure, a very fast coarsening algorithm, and two new local search algorithms. One is a k-way(More)
We develop a multilevel algorithm for hypergraph partitioning that contracts the vertices one at a time. Using several caching and lazy-evaluation techniques during coarsen-ing and refinement, we reduce the running time by up to two-orders of magnitude compared to a naive n-level algorithm that would be adequate for ordinary graph partitioning. The overall(More)
The clinical evaluation of the Cobas Core beta 2-Microglobulin EIA was performed on the random access analyzer Cobas Core. The coefficients of variations for the intra-assay and inter-assay precisions ranged between 3% and 6%. In comparison to healthy persons (0.7-2.7 mg/l), significantly elevated serum levels of beta 2-m were found in patients with(More)
Many problems in computer science can be represented by a graph and reduced to a graph clustering or k-way partitioning problem. In the classical definition, a graph consists of nodes and edges which usually connect exactly two nodes. Hypergraphs are a generalization of graphs, where every edge can connect an arbitrary number of nodes. Recent results(More)
The breast cancer marker Mucin-like Carcinoma-associated Antigen (MCA) was evaluated in a version that has been adapted to a new enzyme immunoanalyser, the Cobas Core. The two-step sandwich assay has a short total assay time of less than 60 minutes. Standard curves are stable for at least 2 weeks. The coefficients of variation for the inter-assay precision(More)
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