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Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs.
Novel series of 2-morpholinoquinoline scaffolds (6a-n), containing the 1,2,4-oxadiazole and moiety, was designed and synthesized in good yield (76-86%). The synthesized compounds were screened forExpand
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Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
A series of novel morpholinoquinoline based conjugates with pyrazoline moiety were synthesized under microwave irradiation. The newly synthesized compounds were screened for their preliminary inExpand
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Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening.
A novel series of fluoro substituted pyrazolylpyrazolines 7a-l was synthesized in good to excellent yield (77-88%) from pyrazole chalcones 5a-d and substituted phenyl hydrazine hydrochlorides 6a-cExpand
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Design, synthesis, and characterization of a fluoro substituted novel pyrazole nucleus clubbed with 1,3,4-oxadiazole scaffolds and their biological applications
A novel series of compounds incorporating a fluoro substituted pyrazole nucleus clubbed with 1,3,4-oxadiazole scaffolds (7a–p) was synthesized in good yields (79–89%). The structures of all theExpand
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Palladium N-heterocyclic carbene catalyzed regioselective C–H halogenation of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones using N-halosuccinimides (NXS)
A novel palladium N-heterocyclic carbene [Pd(NHC)Cl2] complex of vitamin B1 was synthesized and characterized by 1H NMR, EDX, FT-IR and UV–visible spectroscopy. The complex was used as a catalyst forExpand
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Cu(N-heterocyclic carbene)chloride: an efficient catalyst for multicomponent click reaction for the synthesis of 1,2,3-triazoles in water at room temperature
A novel water soluble copper(N-heterocyclic carbene)chloride [Cu(NHC)Cl] complex of vitamin B1 was synthesized and characterized by EDX, FT-IR and NMR spectroscopy. It was employed for threeExpand
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Palladium N-heterocyclic carbene catalyzed regioselective thiolation of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones using aryl thiols
Abstract A palladium N-heterocyclic carbene [Pd(NHC)Cl2] complex of Vitamin B1 developed earlier in our lab was also found to be an effective catalyst for regioselective thiolation via C–H bondExpand
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Green synthesis and pharmacological screening of polyhydroquinoline derivatives bearing a fluorinated 5-aryloxypyrazole nucleus
A novel series of polyhydroquinoline scaffolds 8a–p has been designed and synthesized under ultrasonic irradiation by a one-pot three-component cyclocondensation reaction of 3-methyl-5-substitutedExpand
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Green Synthesis and Pharmacological Screening of Polyhydroquinoline Derivatives Bearing a Fluorinated 5‐Aryloxypyrazole Nucleus.
A series of novel hydroquinoline derivatives (IV) is synthesized under ultrasonic irradiation by a one-pot three-component cyclocondensation reaction of pyrazole carbaldehydes (II) with malononitrileExpand
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