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To evaluate the tumor necrosis factor (TNF) a–e microsatellite polymorphism in Chagasic patients, we studied 162 patients stratified according to the major clinical variants (cardiac, digestive, digestive plus cardiac, and indeterminate forms) and 221 healthy controls. TNF microsatellite alleles were typed using genomic DNA amplified with specific primers.(More)
Acne fulminans is a rare condition and the most severe form of acne. It involves the sudden onset of febrile and multisystemic symptoms, with poor response to ordinary therapy in patients who previously had mild to moderate acne. It is characterized by hemorrhagic ulcerative crusting lesions on the face, chest and upper back. The authors report a case of(More)
AIM To evaluate the demographic characteristics and clinical phenotypes of inflammatory bowel disease (IBD) in a geographic area in Northeastern Brazil. METHODS This retrospective study was conducted at the Hospital of the Federal University of Piauí in Northeastern Brazil. Demographic characteristics and clinical phenotypes of IBD were analyzed in(More)
INTRODUCTION Leprosy is a potentially disabling infectious disease that evolves into emotional issues due to the prejudice that persists about the illness. The endemic has declined substantially with multidrug therapy (MDT) in the 80's; however, new demands associated with the reduction of stigma and the improvement of the affected people's quality of life(More)
OBJECTIVE to investigate the seroprevalence of hepatitis C in crack users in Piauí. METHOD seroepidemiological survey, undertaken in the Psycho-Social Care Centers for Drugs and Alcohol (CAPS AD) in Piauí in the period December 2011 to May 2012. A questionnaire was administered and blood samples were collected for serological research. Fisher's exact test(More)
INTRODUCTION  Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) often have associated changes in craniofacial morphology and distribution of body fat, either alone or in combination. AIM  To correlate cephalometric and anthropometric measures with OSAHS severity by using the apnea-hypopnea index (AHI). METHOD  A retrospective cephalometry(More)
INTRODUCTION Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature. METHODS A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating(More)
Objective The aim of this paper is to analyse the quality of life (QOL) of undergraduate nursing students. Methods A descriptive cross-sectional study with 206 students conducted in July 2013, in the city of Picos/PI, Brazil. Data were collected using the WHOQOL-BREF questionnaire. The Mann-Whitney and Kruskal-Wallis tests were used to analyse the data with(More)
Purpose Identify factors associated with infant mortality by a hierarchical model based on socioeconomic, health care, obstetric and biological determinants in a northeastern Brazilian capital. Methods Observational, retrospective cohort study based on secondary data of births and deaths of infants of mothers living in the city of Teresina. Results Based on(More)
Global concern in relation to child mortality gained visibility with the release of the Millennium Development Goals in 2000 in which the reduction of child mortality is included under goal number four, which proposes to reduce the mortality rate of children under five years by two thirds between 1990 and 2015. Reducing child mortality has been a major(More)