Virginie Le Rolle

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OBJECTIVE Tissue Doppler imaging (TDI) is commonly used to evaluate regional ventricular contraction properties through the analysis of myocardial strain. During the clinical examination, a set of strain signals is acquired concurrently at different locations. However, the joint interpretation of these signals remains difficult. This paper proposes a(More)
The analysis of followup data from patients suffering from heart failure is a difficult task, due to the complex and multifactorial nature of this pathology. In this paper, we present a coupled model, integrating a pulsatile heart into a model of the short to long-term regulations of the cardiovascular system. An interface method is proposed to couple these(More)
A lumped-parameter model of the cardiovascular system is applied in this work to the analysis of the characteristics of mitral flow profiles, for different atrio-ventricular pacing configurations, in the context of cardiac resynchronization therapy (CRT). Primarily, a sensitivity analysis is performed on the main model parameters, so as to discern their(More)
In this paper, we propose the substitution of the original, non-pulsatile cardiac sub-model of the Guyton model by an elastance-based pulsatile model of the heart, including interventricular interaction through the septum. Parameters of this cardiac model were identified by comparing the simulations obtained from the original Guyton model with those(More)
GOAL The goal of this paper is to propose a model-based control design framework, adapted to the development of control modules for medical devices. A particular example is presented in which instantaneous heart rate is regulated in real-time, by modulating, in an adaptive manner, the current delivered to the vagus nerve by a neuromodulator. METHODS The(More)
The evaluation of the time-varying vagal and sympathetic contributions to heart rate remains a challenging task because the observability of the baroreflex is generally limited and the time-varying properties are difficult to take into account, especially in non-stationnary conditions. The objective is to propose a model-based approach to estimate the(More)
Mathematical models of the coronary circulation have been shown to provide useful information for the analysis of intracoronary blood flow and pressure measurements acquired during coronary artery bypass graft (CABG) surgery. Although some efforts towards the patient-specific estimation of model parameters have been presented in this context, they are based(More)
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