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Variable expression levels detected in the Drosophila effectors of piRNA biogenesis.
piRNAs (piwi-interacting RNAs) are a class of small interfering RNAs that play a major role in the regulation of transposable elements (TEs) in Drosophila and are considered of fundamental importance… Expand
Maternally deposited germline piRNAs silence the tirant retrotransposon in somatic cells
Transposable elements (TEs), whose propagation can result in severe damage to the host genome, are silenced in the animal gonad by Piwi‐interacting RNAs (piRNAs). piRNAs produced in the ovaries are… Expand
Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel
- Roel P. J. Bevers, Maria Litovchenko, +5 authors B. Deplancke
- Biology, Medicine
- Nature metabolism
- 1 December 2019
The nature and extent of mitochondrial DNA variation in a population and how it affects traits is poorly understood. Here we resequence the mitochondrial genomes of 169 Drosophila Genetic Reference… Expand
Extensive mitochondrial population structure and haplotype-specific phenotypic variation in the Drosophila Genetic Reference Panel
The Drosophila Genetic Reference Panel (DGRP) serves as a valuable resource to better understand the genetic landscapes underlying quantitative traits. However, such DGRP studies have so far only… Expand
Commensal bacteria act as a broad genetic buffer in Drosophila during chronic under-nutrition
Eukaryotic genomes encode several well-studied buffering mechanisms that robustly maintain invariant phenotypic outcome despite fluctuating environmental conditions. Here we show that the gut… Expand