Virginia Trandafirescu

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BACKGROUND Epidemiological data of renal disease are available from large national renal biopsy registries from Central and Western European countries; in contrast, detailed epidemiological data from Eastern European countries are missing. This report is the first review of histological data, over a period of 10 years (1995-2004), covering a population of(More)
Alterations of the glycosaminoglycans (GAG) from the glomerular basement membrane have been demonstrated in glomerulonephritis (GN) with heavy proteinuria. Experimental data suggest that GAG could be used in the treatment of GN for their antiproteinuric and antiproliferative effects. The aim of this study was to assess the evolution of proteinuria during(More)
Wir stellen eine adipöse (BMI: 39 kg/m2) 45 jährige Frau mit idiopathischer retroperitonealer Fibrose (IRF) und diätetisch eingestellten Diabetes mellitus und Diabetes insipidus vor: Bei einer Routinekontrolle wurde Folgendes erhoben: Serum Kreatinin: 1,74 mg/dl. Es bestand ein "inflammatorisches Syndrom" verbunden mit Fieber. Eine Spiral CT(More)
Systemic lupus erythematosus, an inflammatory disease, has lupus nephritis as severe complication. Hypertension, secondary of the lupus nephritis represents a major cardiovascular risk factor. The impact of hypertension on the evolution and prognosis in lupus nephritis patients as well as the need to initiate pathogenic, antihypertensive and cardiovascular(More)
During the last years renal abscesses are being diagnosed with increasing frequency in Nephrology departments. Progresses achieved in imaging procedures permit a timely diagnosis of renal abscesses. At the same time modern antibiotic therapies permit the treatment of this disease in Nephrology departments. In the current paper we present some specifics of(More)
Lesions of glomerular nephropathy were found in 5 cases of acute trichinosis, characterized by a low proteinuria and hematuria as well as by moderate deficit of the renal function. Renal biopsy revealed lesions of proliferative glomerulitis, while immunofluorescence examination showed granular deposits of IgG and beta1-C-globulin on basement membranes.(More)
Erysipelas is an infectious disease caused by group A beta hemolytical streptococci which may produce renal lesions, most frequently glomerular disease. Renal injury although known is less studied in practice. Rarely bioptical exams have been performed, thus the problem of the relationship erysipelas glomerular disease is practically not solved. The aim of(More)
This paper draws attention to the relationship between the clinical and biological picture of SLE and the immune mechanisms of this disease. The presence, in the same patient, of erythema multiforme-like skin lesions and erythemato-squamous lesions specific for SLE together with a characteristic immune picture (speckled antinuclear antibodies (ANAs),(More)
The paper presents data regarding the compartmentalization of the nephron related to immune processes taking place at this level. The morphofunctional compartments of the nephron (glomerular, tubulo-interstitial and juxtaglomerular) become immune compartments during immune processes. The paper shows the immune cells located in the morphofunctional(More)