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BACKGROUND Although studies of immigrant Asian Indians in other countries show high rates of diabetes (DM), metabolic syndrome (MetS), and cardiovascular disease (CVD), no randomized, population-based studies of this rapidly growing ethnic group exist in the US. METHODS The sample comprised 1038 randomly selected Asian Indian immigrants, aged 18 years and(More)
Indians undergoing socioeconomic and lifestyle transitions will be maximally affected by epidemic of type 2 diabetes (T2D). We conducted a two-stage genome-wide association study of T2D in 12,535 Indians, a less explored but high-risk group. We identified a new type 2 diabetes-associated locus at 2q21, with the lead signal being rs6723108 (odds ratio 1.31;(More)
AIMS To conduct a systematic review and meta-analysis of observational studies in order to assess the association between Type 1 diabetes and fractures. BACKGROUND The risk of fracture in men and women with Type 1 diabetes has not been studied in a large prospective well designed cohort. METHODS Data were selected from Medline and Embase and abstracts(More)
BACKGROUND & OBJECTIVES Information on gastrointestinal manifestations and then response after curative parathyroid surgery is scarce in symptomatic primary hyperparathyroidism (PHPT). This study was carried out to analyse gastrointestinal manifestations in patients with PHPT and their associations with biochemical parameters. METHODS This retrospective(More)
One of the main objectives of the DARPA High Productivity Computing Systems (HPCS) program is to reassess the way we define and measure performance, programmability, portability, robustness and ultimately productivity in the High Performance Computing (HPC) domain. This article describes the Scalable Synthetic Compact Applications (SSCA) benchmark suite, a(More)
BACKGROUND Sexual side effects are commonly associated with serotonin reuptake inhibitor (SRI) therapy. The mechanism underlying SRI-induced sexual dysfunction has been hypothesized to be mediated by direct serotonergic effects. Evidence from open-label reports suggests that cyproheptadine, nefazodone, mirtazapine, and mianserin, which block one or more(More)
As India will ranks first in diabetes now and will continue to do so in 2025, we must prevent the disease by various measures. Before setting the programmes, we should have ample data on the population's knowledge, attitude and practice (KAP) of diabetes. There are some epidemiological studies from southern India, Mumbai and north India, but there is no KAP(More)
Star-P ‡ is an interactive parallel scientific computing environment. It aims to make parallel programming more accessible. Star-P borrows ideas from Matlab*P [3], but is a new development. Currently only a Matlab interface for Star-P is available, but it is not limited to being a parallel Matlab. It combines all four parallel Matlab approaches in one(More)
A rich variety of tools help researchers with high-performance numerical computing, but few tools exist for large-scale combinatorial computing. The authors describe their efforts to build a common infrastructure for numerical and combinatorial computing by using parallel sparse matrices to implement parallel graph algorithms.