Learn More
The goal of this paper is to develop models and methods that use complementary strengths of Mixed Integer Linear Programming (MILP) and Constraint Programming (CP) techniques to solve problems that are otherwise intractable if solved using either of the two methods. The class of problems considered in this paper have the characteristic that only a subset of(More)
The design of a CMOS 22–29-GHz pulse-radar receiver (RX) front-end for ultra-wideband automotive radar sensors is presented. The chip includes a low-noise amplifier, in-phase/quadrature mixers, a quadrature voltage-controlled oscillator (QVCO), pulse formers, and baseband variable-gain amplifiers. Fabricated in a 0.18m CMOS process, the RX front-end chip(More)
Allergen immunotherapy is an effective but underutilized treatment for atopic asthma. We have previously demonstrated that CpG oligodeoxynucleotides (CpG ODN) can prevent the development of a murine model of asthma. In the current study, we evaluated the role of CpG ODN in the treatment of established eosinophilic airway inflammation and bronchial(More)
BACKGROUND Allergic rhinosinusitis is characterized by eosinophilic inflammation of the upper airway, which is induced by TH-2 cytokines. CpG oligodeoxynucleotides (ODN) are known to induce TH-1 and to suppress TH-2 cytokines in a variety of settings, including murine models of asthma. OBJECTIVE To examine the effect of CpG ODN in a murine model of upper(More)
Asthma is a complex polygenic disease involving the interaction of many genes. In this study, we investigated the allergic response in experimental asthma. First, we constructed a biological interaction network using the BOND (Biomolecular Object Network Databank) database of literature curated molecular interactions. Second, we mapped differentially(More)
A W-band direct-detection-based receiver front-end for millimeter-wave passive imaging in a 0.18m BiCMOS process is presented. The proposed system is comprised of a direct-detection front-end architecture employing a balanced LNA with an embedded Dicke switch, power detector, and baseband circuitry. The use of a balanced LNA with an embedded Dicke switch(More)