Vinu Madhusudanannair

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Cor triatriatum dexter is a rare congenital abnormality in which the right atrium is divided into two chambers by a membrane. A rare variant of cor triatriatum dexter where the membrane is attached to the left of the superior vena cava at one end and to the right of inferior vena cava and coronary sinus at the other end has been described only once before.(More)
e16017 Background: SGCs are rare neoplasms with variable clinical behavior where cytotoxic chemotherapy is palliative for some with symptomatic progressive disease, and novel agents have been insufficiently studied. We assessed patients with SGCs in a dedicated phase-I clinical trials clinic in order to determine their outcome. METHODS We reviewed records(More)
Mammalian target of rapamycin (mTOR) inhibitors like temsirolimus may result in undesirable AKT upregulation. Metformin inhibits mTOR through different mechanisms and may enhance temsirolimus’s antitumor activity. We conducted an open-label phase I dose escalation trial of this drug combination in patients with advanced/refractory cancers. Temsirolimus, 25(More)
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