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OBJECTIVE To study the clinical efficacy and the incremental cost-effectiveness of albendazole in improving the nutritional status of pre-school children. DESIGN Single blind, placebo-controlled trial with child as the unit of randomization. SETTING In the Anganwadi centers of the Integrated Child Development Services situated in the urban slums of(More)
BACKGROUND In north India, vitamin A deficiency (retinol <0·70 μmol/L) is common in pre-school children and 2-3% die at ages 1·0-6·0 years. We aimed to assess whether periodic vitamin A supplementation could reduce this mortality. METHODS Participants in this cluster-randomised trial were pre-school children in the defined catchment areas of 8338(More)
OBJECTIVE To assess the point prevalence of intestinal parasites and their association with nutritional parameters. SETTING Anganwadi centers under the Integrated Child Development Scheme (ICDS) in Lucknow, North India. DESIGN Cross-sectional survey. METHODS By random draw, 32 out of 153 Anganwadi centers were selected. All eligible subjects(More)
A cross-sectional survey was conducted in the Integrated Child Development Scheme (ICDS) to assess the sexual behavior patterns and knowledge of sexually transmitted diseases (STDs) among 15-21 year old boys with a goal of developing a community-based reproductive educational health program in India. About 221 boys from 35 Anganwadi centers were(More)
OBJECTIVES To determine the concentrations of blood lead (PbB) in pregnant women in the slums of Lucknow, north India. METHODS Of the 203 designated municipal slums in Lucknow, 70 were randomly selected for study and a cohort of 500 pregnant women was enrolled. Each participant was interviewed with questions on possible sources of exposure to lead,(More)
BACKGROUND In north India many pre-school children are underweight, many have intestinal worms, and 2-3% die at ages 1·0-6·0 years. We used the state-wide Integrated Child Development Service (ICDS) infrastructure to help to assess any effects of regular deworming on mortality. METHODS Participants in this cluster-randomised study were children in(More)
The main objective of this study was to elicit proportional cause specific mortality in the underfives in the urban slums of Lucknow in North India. The families with under five mortality in the 28 randomly selected slums in 1993 were located from the records of the slum health workers and verbal autopsy was conducted to assign a cause of death. There were(More)
OBJECTIVE The study was conducted to assess the effectiveness of six monthly albendazole (ABZ) for improving the weight and height of preschool children when initiated at 0.5-1 year of age in populations with a high transmission rate of intestinal roundworm, Ascaris lumbricoides. It was a cluster randomized trial in the urban slums of Lucknow, North India.(More)
BACKGROUND More than a third of the world's children are infected with intestinal nematodes. Current control approaches emphasise treatment of school age children, and there is a lack of information on the effects of deworming preschool children. METHODOLOGY We studied the effects on the heights and weights of 3,935 children, initially 1 to 5 years of(More)
We recorded the causes of death in the preceding 3 years in a slum population of 24,196 children less than 5 years of age in Lucknow, North India. Of 1469 deaths recorded, 298 were stillbirths. For each death, a 'verbal autopsy' was conducted by interviewing the parents to ascertain the cause of death. 71.8 per cent of deaths were at home; 94.5 per cent of(More)