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BACKGROUND The amino acid substitution model is the core component of many protein analysis systems such as sequence similarity search, sequence alignment, and phylogenetic inference. Although several general amino acid substitution models have been estimated from large and diverse protein databases, they remain inappropriate for analyzing specific species,(More)
More effective mosquito control strategies are urgently required due to the increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the release of insects carrying a dominant lethal allele (RIDL) are two proposed methods for environmentally-friendly, species-targeted population control. These methods may be more suitable for(More)
The DOE [Department of Energy] and its predecessor agencies have had a long history of developing and handling sensitive, classified information. Since the Manhattan Project, identification of classified information has been supported by principles and rules, called " classification topics, " in guidance documents that are published for use by authorized(More)
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