Vineeta Singh

Antonello Bonci4
Shafiul Haque3
C. K. M. Tripathi3
Purva Gupta2
4Antonello Bonci
3Shafiul Haque
3C. K. M. Tripathi
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Stress increases addictive behaviors and is a common cause of relapse. Corticotropin-releasing factor (CRF) plays a key role in the modulation of drug taking by stress. However, the mechanism by which CRF modulates neuronal activity in circuits involved in drug addiction is poorly understood. Here we show that CRF induces a potentiation of NMDAR(More)
Cocaine-induced plasticity of glutamatergic synaptic transmission in the ventral tegmental area (VTA) plays an important role in brain adaptations that promote addictive behaviors. However, the mechanisms responsible for triggering these synaptic changes are unknown. Here, we examined the effects of acute cocaine application on glutamatergic synaptic(More)
Degeneration of dopamine neurons in the substantia nigra pars compacta (SNc) plays an important role in the pathophysiology of neurodegenerative diseases like Parkinsonism and vascular dementia. SNc dopamine neurons both in vitro and in vivo show sensitivity to hypoxic/ischemic conditions and undergo degeneration. In acute brain slices, these dopamine(More)
During the search for a potent antifungal drug, a cell-permeable metabolite was isolated from a soil isolate taxonomically identified as Penicillium radicum. The strain was found to be a potent antifungal agent. Production conditions of the active compound were optimized and the active compound was isolated, purified, characterized and identified as a(More)
Guillain-Barre syndrome (GBS) is a heterogenous group of peripheral-nerve disorders with similar clinical presentation characterized by acute, self-limited, progressive, bilateral and relatively symmetric ascending flaccid paralysis, which peaks in 2-4 weeks and then subsides. The usual complications, which occur in a patient of GBS are pneumonia, sepsis,(More)
Clustering is one of the most important research areas in the field of data mining. In simple words, clustering is a division of data into different groups. Data are grouped into clusters in such a way that data of the same group are similar and those in other groups are dissimilar. It aims to minimize intra-class similarity while to maximize interclass(More)
Infrared pupillometry was introduced in 1962 but portable instruments that use this technology have only recently become available in the hospital setting. Questions surrounding the accuracy of these instruments have been addressed by documenting the inter-observer agreement on pupillary measurements and also by comparisons with standard pen-light(More)
We explore the use of extended pixel representation for color based image segmentation using the K-means clustering algorithm. Various extended pixel representations have been implemented in this paper and their results have been compared. By extending the representation of pixels an image is mapped to a higher dimensional space. Unlike other approaches,(More)
Fungal strain, Aspergillus clavatus MTCC1323 under solid state fermentation was found to produce enzymes (protease, amylase and pectinase) having potential of degrading the biofilms of Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. Maximum specific enzyme activities were found to be 10.0, 8.0, and 10.086 U/mg for protease, amylase and(More)