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Architecture of the fungal nuclear pore inner ring complex
Building a gate to the nucleus Nuclear pore complexes form a gateway between the cytoplasm and the nucleus (see the Perspective by Ullman and Powers). Stuwe et al. combined structural, biochemical,Expand
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  • 7
Architecture of the nuclear pore complex coat
A closeup view of the nuclear pore's coat The precise molecular architecture of the nuclear pore complex (NPC), which mediates traffic between the cytoplasm and the nucleus, has been difficult toExpand
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Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2
  • J. Sun, M. Paduch, +7 authors S. Tan
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences
  • 17 September 2018
Significance Regulating gene expression is critical to the normal function of a biological cell, and misregulation of gene expression often leads to a diseased cell. In eukaryotic cells, DNA geneticExpand
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Design and initial characterization of the SC-200 proteomics standard mixture.
High-throughput (HTP) proteomics studies generate large amounts of data. Interpretation of these data requires effective approaches to distinguish noise from biological signal, particularly asExpand
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THE ROLE OF THE IRE1α PATHWAY IN VASCULAR STIFFENING AND FIBROSIS
...............................................................................................iii Acknowledgements...................................................................................vExpand
Thermoelectric Power in Dual-Gated Bilayer Graphene