Vincent Portero

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SUMMARY Analysing large amounts of data generated by next-generation sequencing (NGS) technologies is difficult for researchers or clinicians without computational skills. They are often compelled to delegate this task to computer biologists working with command line utilities. The availability of easy-to-use tools will become essential with the(More)
  • Camille Rolland-Debord, David Lair, Tiphaine Roussey-Bihouée, Dorian Hassoun, Justine Evrard, Marie-Aude Cheminant +7 others
  • 2014
BACKGROUND Allergic asthma is caused by abnormal immunoreactivity against allergens such as house dust mites among which Dermatophagoides farinae (Der f) is a common species. Currently, immunotherapy is based on allergen administration, which has variable effect from patient to patient and may cause serious side effects, principally the sustained risk of(More)
BACKGROUND The Brugada syndrome is an inherited cardiac arrhythmia associated with high risk of sudden death. Although 20% of patients with Brugada syndrome carry mutations in SCN5A, the molecular mechanisms underlying this condition are still largely unknown. METHODS AND RESULTS We combined whole-exome sequencing and linkage analysis to identify the(More)
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