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  • Derek K Hagman, Lori B Hays, Susan D Parazzoli, Vincent Poitout
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2005 (First Publication: 16 September 2005)
  • Abnormalities in lipid metabolism have been proposed as contributing factors to both defective insulin secretion from the pancreatic beta cell and peripheral insulin resistance in type 2 diabetes.Expand
  • Raphaël Roduit, Christopher W. Nolan, +11 authors Marc Prentki
  • Biology, Medicine
  • Diabetes
  • 2004 (First Publication: 1 April 2004)
  • The malonyl-CoA/long-chain acyl-CoA (LC-CoA) model of glucose-induced insulin secretion (GIIS) predicts that malonyl-CoA derived from glucose metabolism inhibits fatty acid oxidation, therebyExpand