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  • Camille Godon, Fabrice P. Cordelières, +4 authors Vincent Favaudon
  • Biology, Medicine
  • Nucleic acids research
  • 2008 (First Publication: 27 June 2008)
  • The consequences of PARP-1 disruption or inhibition on DNA single-strand break repair (SSBR) and radio-induced lethality were determined in synchronized, isogenic HeLa cells stably silenced or notContinue Reading
  • Valentin Calugaru, C Nauraye, Georges Noël, Nicole Giocanti, Vincent Favaudon, Frédérique Mégnin-Chanet
  • Medicine
  • International journal of radiation oncology…
  • 2011 (First Publication: 1 November 2011)
  • PURPOSE Treatment planning in proton therapy uses a generic value for the relative biological efficiency (RBE) of 1.1 throughout the spread-out Bragg peak (SOBP) generated. In this article, we reportContinue Reading
  • Aurélie Joubert, Kristin M. Zimmerman, +5 authors Nicolas Foray
  • Biology, Medicine
  • International journal of radiation biology
  • 2008 (First Publication: 1 January 2008)
  • Purpose: Human diseases associated with acute radiation responses are rare genetic disorders with common clinical and biological features including radiosensitivity, genomic instability, chromosomalContinue Reading
  • Fernando P. Molina-Heredia, Chantal Houée-Lévin, +5 authors Vincent Nivière
  • Chemistry, Physics, Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2006 (First Publication: 3 October 2006)
  • The superoxide radical O2·̅ is a toxic by-product of oxygen metabolism. Two O2·̅ detoxifying enzymes have been described so far, superoxide dismutase and superoxide reductase (SOR), both forming H2O2Continue Reading
  • Vincent Favaudon, Hervé Tourbez, Chantal Houée-Lévin, Jean Marc Lhoste
  • Chemistry, Medicine
  • Biochemistry
  • 1990 (First Publication: 1 December 1990)
  • Disulfide bond reduction by the CO2.- radical was investigated in aponeocarzinostatin, aporiboflavin-binding protein, and bovine immunoglobulin. Protein-bound cysteine free thiols were formed underContinue Reading
  • Pierre Montay-Gruel, Kristoffer Petersson, +9 authors Marie-Catherine Vozenin
  • Medicine
  • Radiotherapy and oncology : journal of the…
  • 2017 (First Publication: 22 May 2017)
  • This study shows for the first time that normal brain tissue toxicities after WBI can be reduced with increased dose rate. Spatial memory is preserved after WBI with mean dose rates above 100Gy/s,Continue Reading