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Preclinical evaluation and molecular docking of 2, 5-di-tert-butyl-1, 4-benzoquinone (DTBBQ) from Streptomyces sp. VITVSK1 as a potent antibacterial agent
- Vinay Gopal Jannu, P. Sanjenbam, K. Kannabiran
- Biology, Computer Science
- Int. J. Bioinform. Res. Appl.
- 1 March 2015
The incidence of bacterial disease has increased tremendously in the last decade, because of the emergence of drug resistance strains within the bacterial pathogens. Expand
Heterologous expression of the trichostatin gene cluster and functional characterization of N-methyltransferase TsnB8.
- Wei-ning Liu, Vinay Gopal Jannu, +6 authors Yiguang Zhu
- Chemistry, Medicine
- Organic & biomolecular chemistry
- 1 May 2020
Trichostatins are potent inhibitors of histone deacetylase (HDAC). In this work, a new trichostatin derivative isotrichostatin RK (1) and five known compounds trichostatin RK (2), JBIR-111 (3), 9179B… Expand