Vilmos Vécsei

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OBJECTIVE The aim of the present study was the investigation of differential gene expression in primary human articular chondrocytes (HACs) and in cultivated cells derived from HACs. DESIGN Primary human articular chondrocytes (HACs) isolated from non-arthritic human articular cartilage and monolayer cultures of HACs were investigated by(More)
To evaluate articular cartilage repair tissue after biological cartilage repair, we propose a new technique of non-invasive, high-resolution magnetic resonance imaging (MRI) and define a new classification system. For the definition of pertinent variables the repair tissue of 45 patients treated with three different techniques for cartilage repair(More)
OBJECTIVE A multicenter trial analyzed complications and odds for complications in open and closed tibial fractures stabilized by small diameter nails. DESIGN Retrospective. SETTING Four Level I trauma centers. PATIENTS Four hundred sixty-seven tibial fractures were included in the study. There were fifty-two proximal fractures, 219 midshaft(More)
STUDY DESIGN A retrospective, comparative study. SUMMARY OF BACKGROUND DATA AND OBJECTIVES Anterior screw fixation has become an accomplished treatment option for the management of odontoid fractures. In younger patients, it has shown encouraging results with low complication rates; whereas in geriatric trauma victims, it remains the subject of(More)
The analysis of 310 cases of fractures of the femur, treated with a Gamma-nail osteosynthesis, done in two clinics for trauma surgery in Vienna, revealed to a high number of complications. For this reason we decided to start an evaluation aming at complications in connection to this type of treatment, with 440 patients treated over a five year period. We(More)
BACKGROUND The continuous increase in the number of fractures of the proximal femur is directly attributable to the worldwide increase in life expectancy. The standard version of the Gamma Interlocking-Nail (standard Gamma nail [SGN], 200-mm length, 10-degree valgus curvature, two distal locking bolts) was designed because of the demands in orthopedic hip(More)
BACKGROUND: Osteochondritis dissecans is a localized condition or injury affecting an articular surface that involves separation of a segment of cartilage and subchondral bone. METHODS: This article discusses the etiology, anatomy, evaluation, classification and treatment of osteochondritis dissecans lesions in the knee joint. RESULTS: Osteochondritis(More)
Articular cartilage in adults has a limited capacity for self-repair after a substantial injury. Surgical therapeutic efforts to treat cartilage defects have focused on delivering new cells capable of chondrogenesis into the lesions. Autologous chondrocyte transplantation (ACT) is an advanced cell-based orthobiologic technology used for the treatment of(More)
We compared the changes in the ratio of type-I and type-II collagen in monolayer cultures of human articular chondrocytes (HAC). HAC were isolated from samples of cartilage from normal joints and cultivated in monolayer for up to 46 days. Expression of collagen type-I and type-II was determined by immunocytochemistry, Western blotting, and the nested(More)
OBJECTIVE Monitoring of articular cartilage repair after matrix-associated autologous chondrocyte implantation (MACI) by a new grading and point-scale system based on noninvasive cartilage-specific magnetic resonance imaging (MRI) protocol. PATIENTS AND METHODS In 20 patients, postoperative high-resolution MRI follow-up examinations at 4, 12, 24 and 52(More)