Vilija Kuraite

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Nicotinic acetylcholine receptors contribute to the mediation of cholinergic role in attention, vigilance, orienting and detection of behavioral significant stimuli. We have recently demonstrated an increase of the intrinsic recurrent excitatory activity of the tectum column caused by the phasic (after-burst) nicotinic potentiation of a frog single axon(More)
It is well established that cholinergic modulation of functioning of neuronal networks is common in the central nervous system at all scales from neuronal columns to large nuclei. It is involved in various attentional, cognitive and behavioral performances. We have recently demonstrated that a frog retinotectal transmission exhibits after-burst (phasic)(More)
Neurons may release more than one classical neurotransmitter (co-mediator). It has been demonstrated in a recent study that a burst of action potentials in frog retina ganglion cells induces an after-burst increase (phasic potentiation) of the retinotectal transmission that lasts tens of seconds. This increase is mediated by presynaptic nicotinic(More)
It was demonstrated in our previous studies of the frog retinotectal transmission that retinotectal synaptic potentials are enhanced by a factor of 1.5 due to the tonic presynaptic nicotinic potentiation, caused by the ambient level of the acetylcholine in the frog tectum. Furthermore, the results of those studies have indicated that the mechanism of the(More)
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