Viktoria D. Mayr

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OBJECTIVE To assess the effects of arginine vasopressin (AVP) on hemodynamic, clinical, and laboratory variables and to determine its adverse side effects in advanced vasodilatory shock. DESIGN Retrospective study. PATIENTS A total of 316 patients. INTERVENTIONS AVP infusion (4 units/hr). MEASUREMENTS AND MAIN RESULTS Cardiocirculatory, laboratory,(More)
BACKGROUND Many surgical interventions worldwide are performed in developing countries. To improve survival of acutely and critically ill patients in these countries, basic problems and demands of anesthesia care need to be identified. Using this survey, we evaluated the current status of anesthesia and its allied disciplines (intensive care medicine,(More)
To evaluate the association between arterial blood pressure (ABP) during the first 24 h and mortality in sepsis. Retrospective cohort study. Multidisciplinary intensive care unit (ICU). A total of 274 septic patients. None. Hemodynamic, and laboratory parameters were extracted from a PDMS database. The hourly time integral of ABP drops below clinically(More)
UNLABELLED In a porcine model of uncontrolled hemorrhagic shock, we evaluated the effects of vasopressin versus an equal volume of saline placebo versus fluid resuscitation on hemodynamic variables and short-term survival. Twenty-one anesthetized pigs were subjected to severe liver injury. When mean arterial blood pressure was <20 mm Hg and heart rate(More)
OBJECTIVE To compare the course of arginine vasopressin (AVP) and copeptin plasma concentrations between patients with infection, severe sepsis, and septic shock. DESIGN Prospective, closed-cohort study. SETTING Twelve-bed general and surgical intensive care unit and 33-bed internal medicine ward in a university hospital. PATIENTS Ten patients with(More)
CONTEXT Determination of arginine vasopressin (AVP) concentrations may be helpful to guide therapy in critically ill patients. A new assay analyzing copeptin, a stable peptide derived from the AVP precursor, has been introduced. OBJECTIVE Our objective was to determine plasma copeptin concentrations. DESIGN We conducted a post hoc analysis of plasma(More)
OBJECTIVE To evaluate the effects of two arginine vasopressin (AVP) dose regimens (0.033 vs. 0.067 IU/min) on treatment efficacy, hemodynamic response, prevalence of adverse events, and changes in laboratory variables. DESIGN Retrospective, controlled study. PATIENTS A total of 78 patients with vasodilatory shock (mean norepinephrine dosage, 1.07(More)
Arginine vasopressin (AVP) has been employed successfully during cardiopulmonary resuscitation, but there exist only few data about the effects of AVP infusion for cardiovascular failure during the post-cardiac arrest period. Cardiovascular failure is one of the main causes of death after successful resuscitation from cardiac arrest. Although the(More)
BACKGROUND The purpose of this study was to investigate the effects of vasopressin versus epinephrine, and both drugs combined, in a porcine model of simulated adult asphyxial cardiac arrest. METHODS AND RESULTS At approximately 7 minutes after the endotracheal tube had been clamped, cardiac arrest was present in 24 pigs and remained untreated for another(More)
To compare the effects of two arginine vasopressin (AVP) dose regimens on the hemodynamic response, catecholamine requirements, AVP plasma concentrations, organ function and adverse events in advanced vasodilatory shock. In this prospective, controlled, open-label trial, patients with vasodilatory shock due to sepsis, systemic inflammatory response syndrome(More)