Vikarm Modak

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OBJECTIVE Evaluating intracranial complications of otitis media. DESIGN An Evaluative study of 106 cases of intracranial complications secondary to otitis media. INTERVENTION Diagnosis is based on history, clinical exam (general, systemic and ENT), investigations hemogram, X-ray mastoid CT scan brain and mastoid. TREATMENT Medical management:IV Higher(More)
The novel 4-(4-oxo-2-arylthiazolidin-3-yl)benzenesulfonamide derivatives were designed and synthesized for selective carbonic anhydrase IX (CA IX) inhibitory activity with anticancer potential. In the CA inhibition assay, 3f was found to be the most potent and selective inhibitor of CA IX with inhibitory constant (K(I)) value of 2.2 nM. Among the(More)
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