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- Publications
- Influence
Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action.
- Renuka Mani, Vijayakumar Natesan
- Chemistry, Medicine
- Phytochemistry
- 2018
In recent years, public and scientific interest in plant flavonoids has tremendously increased because of their postulated health benefits. This review was mainly focuses on the flavone chrysin… Expand
Clinical aspects of urea cycle dysfunction and altered brain energy metabolism on modulation of glutamate receptors and transporters in acute and chronic hyperammonemia.
- Vijayakumar Natesan, Renuka Mani, Ramakrishnan Arumugam
- Biology, Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 July 2016
In living organisms, nitrogen arise primarily as ammonia (NH3) and ammonium (NH4(+)), which is a main component of the nucleic acid pool and proteins. Although nitrogen is essential for growth and… Expand
Neuroprotective effect of chrysin on hyperammonemia mediated neuroinflammatory responses and altered expression of astrocytic protein in the hippocampus.
- Renuka Mani, Vijayakumar Natesan, Ramakrishnan Arumugam
- Chemistry, Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 April 2017
Neuroinflammation is an innate immune response in the central nervous system (CNS) against metabolic and pathogenic toxic wastes. The main hypothesis implies that a state of hyperammonemia which is… Expand
Effect of naringin on ammonium chloride-induced hyperammonemic rats: A dose-dependent study
- Ramakrishnan Arumugam, Vijayakumar Natesan, Renuka Mani
- Chemistry
- 1 September 2016
Abstract Introduction In mammals, ammonia is primarily a toxin that affects the central nervous system, leading to liver damage and urea cycle disorder. Increased accumulation of ammonia results in a… Expand
Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis
- Prabhakar Yellanur Konda, Vijayakumar Poondla, +16 authors Vijayakumar Natesan
- Medicine
- Scientific reports
- 9 October 2020
The high fat diet alters intestinal microbiota due to increased intestinal permeability and susceptibility to microbial antigens leads to metabolic endotoxemia. But probiotic juices reported for… Expand
07.11: Rotational behavior of cold formed steel beams connected through clip angles
- Vijayakumar Natesan, M. Madhavan
- Materials Science
- 1 September 2017
Structural performance on bolted sleeved connections between two CFS channel sections subjected to combined bending and shear
- Vijayakumar Natesan, M. Madhavan
- Materials Science
- 1 August 2019
Abstract An experimental investigation was carried out to study the behavior of the sleeve connection between two cold-formed steel (CFS) channel sections subjected to combined bending and shear. A… Expand
Experimental study of clip angle bolted connection between two cold-formed steel channels
- Vijayakumar Natesan, M. Madhavan
- Materials Science
- 21 August 2020
An experimental investigation was conducted to study the load–deflection relationships, ultimate load and behaviour of beam-to-beam cold-formed steel (CFS) channels connected with clip angles using...
Effect of staggered bolted connections on CFS channel sections
- Bharath Shanmugasundaram, Vijayakumar Natesan, M. Madhavan
- Mathematics
- 1 October 2020
Abstract This research focuses on the effect of staggered bolted connections on the ultimate tensile capacity and failure modes of the cold-formed steel channel sections connected to the gusset… Expand
Molecular docking studies of natural compounds of naringin on enzymes involved in the urea cycle pathway in hyperammonemia
- Ramakrishnan Arumugam, Renuka Mani, Amalan Venkatesan, Senthilmurugan Sengamalai, Vijayakumar Natesan, S. Kim
- Chemistry
- 26 June 2020
Purpose: To investigate the anti-hyperammonemic activity of naringin by molecular docking via in silico studies.Methods: Urea cycle proteins were docked to the natural compound naringin as well as a… Expand